# Reading list

> Reading list | Alliance Aesthetics — The Alliance Aesthetics reading list: collagen cultures, topical GHK research, skin penetration and the combination hair trial.

**Reading room**

The experiments and reviews behind these essays, grouped here by the questions they address.

## The collagen cultures

Start with the [collagen-synthesis experiment in human fibroblast cultures](https://pubmed.ncbi.nlm.nih.gov/3169264/), then the [tissue-remodeling review](https://pubmed.ncbi.nlm.nih.gov/18644225/) and the [skin-regeneration review](https://pmc.ncbi.nlm.nih.gov/articles/PMC4508379/). I value the experiment's narrow observation and the reviews' broader account for different reasons.

## Topical delivery and skin outcomes

The [skin-layer penetration study](https://pmc.ncbi.nlm.nih.gov/articles/PMC3016279/) concerns copper passage and retention. The [anti-wrinkle review](https://pmc.ncbi.nlm.nih.gov/articles/PMC11830136/) brings the delivery challenge together with reported topical results. These are the central entries for the [skin-barrier](/skin-barrier) and [skin-results](/skin-results) essays.

## The hair preparations

Read the [GHK and 5-aminolevulinic acid trial](https://pmc.ncbi.nlm.nih.gov/articles/PMC4969472/) alongside the [AHK-Cu follicle and cell study](https://pubmed.ncbi.nlm.nih.gov/17703734/). The first tested a combination in men; the second examined a copper-peptide analog in human follicles and cells outside the body. Their distinction is the subject of the [hair essay](/hair-complex).

## References

[1] Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ https://pubmed.ncbi.nlm.nih.gov/3169264/
[2] The human tri-peptide GHK and tissue remodeling https://pubmed.ncbi.nlm.nih.gov/18644225/
[3] GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration https://pmc.ncbi.nlm.nih.gov/articles/PMC4508379/
[4] Human skin penetration of a copper tripeptide in vitro as a function of skin layer https://pmc.ncbi.nlm.nih.gov/articles/PMC3016279/
[5] Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective https://pmc.ncbi.nlm.nih.gov/articles/PMC11830136/
[6] Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth https://pmc.ncbi.nlm.nih.gov/articles/PMC4969472/
[7] The effect of tripeptide-copper complex on human hair growth in vitro https://pubmed.ncbi.nlm.nih.gov/17703734/

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At Alliance Aesthetics I put copper-peptide partnerships through their paces against published research; this editorial site is not a business and supplies no medical advice.